Description
Human DAPK1 Recombinant Protein (N-His)
Human DAPK1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg332-Arg679, with an N-terminal His tag. Predicted molecular weight: 40.36 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Death-associated protein kinase 1 is a ~160 kDa protein. Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. For research use only.
Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells.
| Product Name: | Human DAPK1 Recombinant Protein (N-His) |
| SKU: | GXRP10799 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | DAP kinase 1, DAPK, DAPK1, Death-associated protein kinase 1, EC:2.7.11.1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg332-Arg679 |
| Calculated MW: | 40.36 kDa |
| UniProt: | P53355 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
