Description
Human DCD Recombinant Protein (N-His)
Human DCD Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Cys18-Leu110, with an N-terminal His tag. Predicted molecular weight: 11.73 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Dermcidin (DCD) is a ~11 kDa protein. Found in sweat, has an antimicrobial activity during early bacterial colonization. For research use only.
The secreted peptide assembles into homohexameric complexes that can associate with and also insert into pathogen membranes. Once inserted in bacteria membranes forms anion channels probably altering the transmembrane potential essential for bacterial survival. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat.
| Product Name: | Human DCD Recombinant Protein (N-His) |
| SKU: | GXRP01968 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | DCD, AIDD, DSEP, Dermcidin, Preproteolysin |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Cys18-Leu110 |
| Calculated MW: | 11.73 kDa |
| UniProt: | P81605 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
