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Human DCX Recombinant Protein (N-His)
Key Features

Human DCX Recombinant Protein (N-His) (GXRP13549)

SKU GXRP13549
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human DCX Recombinant Protein (N-His)

Human DCX Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala52-Gly276, with an N-terminal His tag. Predicted molecular weight: 27.82 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Neuronal migration protein doublecortin is a ~40 kDa protein. Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. For research use only.

May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.

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