Description
Human DDX39A Recombinant Protein (N-His)
Human DDX39A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg47-Arg427, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. ATP-dependent RNA helicase DDX39A is a ~49 kDa protein. Helicase that plays an essential role in mRNA export and is involved in multiple steps in RNA metabolism including alternative splicing. For research use only.
Regulates nuclear mRNA export to the cytoplasm through association with ECD. Also involved in spliceosomal uridine-rich small nuclear RNA (U snRNA) export by stimulating the RNA binding of adapter PHAX. Plays a role in the negative regulation of type I IFN production by increasing the nuclear retention of antiviral transcripts and thus reducing their protein expression. Independently of the interferon pathway, plays an antiviral role against alphaviruses by binding to a 5' conserved sequence element in the viral genomic RNA.
| Product Name: | Human DDX39A Recombinant Protein (N-His) |
| SKU: | GXRP13651 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ATP-dependent RNA helicase DDX39A, DDX39, DDX39A, DEAD box protein 39, EC:3.6.4.13, Nuclear RNA helicase URH49 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg47-Arg427 |
| UniProt: | O00148 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
