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Human DEFA3 Recombinant Protein (N-GST)
Key Features

Human DEFA3 Recombinant Protein (N-GST) (GXRP01869)

SKU GXRP01869
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-GST
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human DEFA3 Recombinant Protein (N-GST)

Human DEFA3 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Pro21-Cys94, with an N-terminal GST tag. Predicted molecular weight: 34.98 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Neutrophil defensin 3 (DEFA3) is a ~10 kDa protein. Effector molecule of the innate immune system that acts via antibiotic-like properties against a broad array of infectious agents including bacteria, fungi, and viruses. For research use only.

Possesses the ability to neutralize bacterial toxins such as B.anthracis lethal factor, Clostridium difficile cytotoxin B as well as leukocidin produced by Staphylococcus aureus. Also blocks herpes simplex virus infection by interacting with envelope glycoprotein B and thus preventing its binding to heparan sulfate, the receptor for attachment.

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