Description
Human DEFB126 Recombinant Protein (N-GST)
Human DEFB126 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Asn21-Gly111, with an N-terminal GST tag. Predicted molecular weight: 36.83 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Beta-defensin 126 (DEFB126) is a ~12 kDa protein. Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. For research use only.
Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other surface components and allows sperm to penetrate the cumulus matrix and bind to the zona pellucida of the oocyte. In vitro has antimicrobial activity and may inhibit LPS-mediated inflammation.
| Product Name: | Human DEFB126 Recombinant Protein (N-GST) |
| SKU: | GXRP02825 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | C20orf8, Epididymal secretory protein 13.2, DEFB26, Beta-defensin 26, Beta-defensin 126, DEFB126, HBD26, ESP13.2, DEFB-26, Defensin, beta 126 |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Asn21-Gly111 |
| Calculated MW: | 36.83 kDa |
| UniProt: | Q9BYW3 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
