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Human DIAPH1 Recombinant Protein (N-His)
Key Features

Human DIAPH1 Recombinant Protein (N-His) (GXRP00206)

SKU GXRP00206
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human DIAPH1 Recombinant Protein (N-His)

Human DIAPH1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp389-Pro583, with an N-terminal His tag. Predicted molecular weight: 24.44 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Protein diaphanous homolog 1 (DIAPH1) is a ~141 kDa protein. Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers. For research use only.

Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and promote cell migration.

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