Description
Human DLG5 Recombinant Protein (N-His)
Human DLG5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp1722-Asn1905, with an N-terminal His tag. Predicted molecular weight: 23.38 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Disks large homolog 5 (DLG5) is a ~213 kDa protein. Acts as a regulator of the Hippo signaling pathway. For research use only.
Negatively regulates the Hippo signaling pathway by mediating the interaction of MARK3 with STK3/4, bringing them together to promote MARK3-dependent hyperphosphorylation and inactivation of STK3 kinase activity toward LATS1. Positively regulates the Hippo signaling pathway by mediating the interaction of SCRIB with STK4/MST1 and LATS1 which is important for the activation of the Hippo signaling pathway. Involved in regulating cell proliferation, maintenance of epithelial polarity, epithelial-mesenchymal transition (EMT), cell migration and invasion. Plays an important role in dendritic spine formation and synaptogenesis in cortical neurons; regulates synaptogenesis by enhancing the cell surface localization of N-cadherin.
| Product Name: | Human DLG5 Recombinant Protein (N-His) |
| SKU: | GXRP02616 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Discs large protein P-dlg, Disks large homolog 5, KIAA0583, Placenta and prostate DLG, DLG5, PDLG |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp1722-Asn1905 |
| Calculated MW: | 23.38 kDa |
| UniProt: | Q8TDM6 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
