Description
Human DSP Recombinant Protein (N-His)
Human DSP Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe2609-Ala2822, with an N-terminal His tag. Predicted molecular weight: 25.56 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Desmoplakin (DSP) is a ~331 kDa protein. A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. For research use only.
Critical for cell-cell adhesion in early stage blastocysts and progression through proamniotic cavity formation. Not required for preimplantation morphogenic process in blastocysts. Required for keratin filament anchoring at the desmosome junction and subsequent organization of the keratin intermediate filament network within the cytoplasm. Required for anchoring of desmosomes to the microtubule architecture, via its interaction with NIN.
| Product Name: | Human DSP Recombinant Protein (N-His) |
| SKU: | GXRP01028 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 250/210 kDa paraneoplastic pemphigus antigen, Desmoplakin, DSP, DP |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Phe2609-Ala2822 |
| Calculated MW: | 25.56 kDa |
| UniProt: | P15924 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
