Description
Human DUSP6 Recombinant Protein (N-His)
Human DUSP6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu347, with an N-terminal His tag. Predicted molecular weight: 40.74 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Dual specificity protein phosphatase 6 (DUSP6) is a ~42 kDa protein. Dual specificity protein phosphatase, which mediates dephosphorylation and inactivation of MAP kinases. For research use only.
Has a specificity for the ERK family. Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia. Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain.
| Product Name: | Human DUSP6 Recombinant Protein (N-His) |
| SKU: | GXRP02394 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Mitogen-activated protein kinase phosphatase 3, MKP3, DUSP6, PYST1, MAP kinase phosphatase 3, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, MKP-3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Leu347 |
| Calculated MW: | 40.74 kDa |
| UniProt: | Q16828 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
