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Human E2F6 Recombinant Protein (N-His)
Key Features

Human E2F6 Recombinant Protein (N-His) (GXRP07416)

SKU GXRP07416
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human E2F6 Recombinant Protein (N-His)

Human E2F6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Pro62-Glu237, with an N-terminal His tag. Predicted molecular weight: 22.26 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Transcription factor E2F6 is a ~31 kDa protein. Inhibitor of E2F-dependent transcription. For research use only.

Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression.

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