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Human EFNB2 Recombinant Protein (N-His)
Key Features

Human EFNB2 Recombinant Protein (N-His) (GXRP01776)

SKU GXRP01776
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human EFNB2 Recombinant Protein (N-His)

Human EFNB2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ile28-Ala229, with an N-terminal His tag. Predicted molecular weight: 24.49 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ephrin-B2 (EFNB2) is a ~36 kDa protein. Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. For research use only.

Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration.

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