Description
Human ELANE Recombinant Protein (N-GST)
Human ELANE Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Ile30-Gln247, with an N-terminal GST tag. Predicted molecular weight: 50.12 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Neutrophil elastase (ELANE) is a ~28 kDa protein. Serine protease that modifies the functions of natural killer cells, monocytes and granulocytes. For research use only.
Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Promotes cleavage of GSDMB, thereby inhibiting pyroptosis. Promotes blood coagulation. Through the activation of the platelet fibrinogen receptor integrin alpha-IIb/beta-3, potentiates platelet aggregation induced by a threshold concentration of cathepsin G (CTSG).
| Product Name: | Human ELANE Recombinant Protein (N-GST) |
| SKU: | GXRP00710 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Medullasin, ELA2, ELANE, PMN elastase, Neutrophil elastase, HLE, Human leukocyte elastase, Elastase-2, Bone marrow serine protease |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Ile30-Gln247 |
| Calculated MW: | 50.12 kDa |
| UniProt: | P08246 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
