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Human EPOR Recombinant Protein (C-His)
Key Features

Human EPOR Recombinant Protein (C-His) (GXRP08987)

SKU GXRP08987
Product Type Recombinant Protein
Species Human
Expression System Mammalian cells
Tag C-His
$577 - $4,138

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Description

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Human EPOR Recombinant Protein (C-His)

Human EPOR Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Ala25-Pro250, with a C-terminal His tag. Predicted molecular weight: 27.73 kDa. Purity: >95% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Erythropoietin receptor is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. For research use only.

Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

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