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Human ERCC2 Recombinant Protein (N-His)
Key Features

Human ERCC2 Recombinant Protein (N-His) (GXRP10686)

SKU GXRP10686
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human ERCC2 Recombinant Protein (N-His)

Human ERCC2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Cys489-Leu760, with an N-terminal His tag. Predicted molecular weight: 33.38 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. General transcription and DNA repair factor IIH helicase subunit XPD is a ~86 kDa protein. ATP-dependent 5'-3' DNA helicase. For research use only.

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, not absolutely essential for minimal transcription in vitro. Required for transcription-coupled nucleotide excision repair (NER) of damaged DNA; recognizes damaged bases. Sequestered in chromatin on UV-damaged DNA. When complexed to CDK-activating kinase (CAK), involved in transcription by RNA polymerase II.

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