Description
Human ERCC2 Recombinant Protein (N-His)
Human ERCC2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala404-Leu637, with an N-terminal His tag. Predicted molecular weight: 28.49 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. General transcription and DNA repair factor IIH helicase subunit XPD (ERCC2) is a ~86 kDa protein. ATP-dependent 5'-3' DNA helicase. For research use only.
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, not absolutely essential for minimal transcription in vitro. Required for transcription-coupled nucleotide excision repair (NER) of damaged DNA; recognizes damaged bases. Sequestered in chromatin on UV-damaged DNA. When complexed to CDK-activating kinase (CAK), involved in transcription by RNA polymerase II.
| Product Name: | Human ERCC2 Recombinant Protein (N-His) |
| SKU: | GXRP03396 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | TFIIH basal transcription factor complex 80 kDa subunit, DNA repair protein complementing XP-D cells, General transcription and DNA repair factor IIH helicase subunit XPD, XPD, ERCC2, TFIIH p80, CXPD, BTF2 p80, TFIIH 80 kDa subunit, DNA excision repair protein ERCC-2, TFIIH subunit XPD, XPDC, Basic transcription factor 2 80 kDa subunit, Xeroderma pigmentosum group D-complementing protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ala404-Leu637 |
| Calculated MW: | 28.49 kDa |
| UniProt: | P18074 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
