Description
Human FBXO45 Recombinant Protein (N-His)
Human FBXO45 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser41-Gly286, with an N-terminal His tag. Predicted molecular weight: 29.95 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. F-box/SPRY domain-containing protein 1 (FBXO45) is a ~30 kDa protein. Component of E3 ubiquitin ligase complex consisting of FBXO45, MYCBP2 and SKP1. For research use only.
Functions in substrate recognition but also plays an important role in assembly of the complex. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Regulates neuron migration during brain development through interaction with N-cadherin/CDH2 after secretion via a non-classical mechanism. Plays a role in the regulation of neurotransmission at mature neurons.
| Product Name: | Human FBXO45 Recombinant Protein (N-His) |
| SKU: | GXRP07530 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | F-box/SPRY domain-containing protein 1, F-box only protein 45, hFbxo45, FBXO45, FBX45 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser41-Gly286 |
| Calculated MW: | 29.95 kDa |
| UniProt: | P0C2W1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
