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Human FGL1 Recombinant Protein (C-His)
Key Features

Human FGL1 Recombinant Protein (C-His) (GXRP09003)

SKU GXRP09003
Product Type Recombinant Protein
Species Human
Expression System Mammalian cells
Tag C-His
€437 - €3,135

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Description

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Human FGL1 Recombinant Protein (C-His)

Human FGL1 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Leu23-Ile312, with a C-terminal His tag. Predicted molecular weight: 36.91 kDa. Purity: >95% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Fibrinogen-like protein 1 is a ~36 kDa protein. Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a ligand of LAG3. For research use only.

LAG3-binding initiates a signaling that inhibits the T-cell receptor (TCR) in the immunological synapse, preventing T-cell activation. Binds LAG3 independently from MHC class II (MHC-II). Secreted by, and promotes growth of, hepatocytes.

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