Description
Human FOLR2 Recombinant Protein (N-His)
Human FOLR2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr17-Asn230, with an N-terminal His tag. Predicted molecular weight: 27.09 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Folate receptor beta (FOLR2/FR-β) is a ~29 kDa protein. Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. For research use only.
Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
| Product Name: | Human FOLR2 Recombinant Protein (N-His) |
| SKU: | GXRP00968 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | FBP, FOLR2, Folate receptor beta, Placental folate-binding protein, Folate receptor, fetal/placental, FR-beta, Folate receptor 2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr17-Asn230 |
| Calculated MW: | 27.09 kDa |
| UniProt: | P14207 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
