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Human GATA3 Recombinant Protein (N-His)
Key Features

Human GATA3 Recombinant Protein (N-His) (GXRP10631)

SKU GXRP10631
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human GATA3 Recombinant Protein (N-His)

Human GATA3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly260-Ser370, with an N-terminal His tag. Predicted molecular weight: 14.75 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Trans-acting T-cell-specific transcription factor GATA-3 is a ~47 kDa protein. Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. For research use only.

Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression. Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33.

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