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Human GCGR Recombinant Protein (N-His)
Key Features

Human GCGR Recombinant Protein (N-His) (GXRP12466)

SKU GXRP12466
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human GCGR Recombinant Protein (N-His)

Human GCGR Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala26-Lys136, with an N-terminal His tag. Predicted molecular weight: 15.35 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Glucagon receptor is a ~54 kDa protein. G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. For research use only.

Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase.

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