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Human GRIK2 Recombinant Protein (N-His)
Key Features

Human GRIK2 Recombinant Protein (N-His) (GXRP02145)

SKU GXRP02145
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human GRIK2 Recombinant Protein (N-His)

Human GRIK2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn286-Pro561, with an N-terminal His tag. Predicted molecular weight: 33.3 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Glutamate receptor ionotropic, kainate 2 (GRIK2) is a ~102 kDa protein. Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. For research use only.

L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformational change leading to the opening of the cation channel, converting the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Modulates cell surface expression of NETO2.

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