Description
Human GRSF1 Recombinant Protein (N-His)
Human GRSF1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val149-Ser335, with an N-terminal His tag. Predicted molecular weight: 24.05 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. G-rich sequence factor 1 is a ~53 kDa protein. Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. For research use only.
Binds RNAs containing the 14 base G-rich element. Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences. Involved in the degradosome-mediated decay of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. Acts by unwinding G-quadruplex RNA structures in MT-ncRNA, thus facilitating their degradation by the degradosome.
| Product Name: | Human GRSF1 Recombinant Protein (N-His) |
| SKU: | GXRP09570 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | G-rich sequence factor 1; GRSF-1; GRSF1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Val149-Ser335 |
| Calculated MW: | 24.05 kDa |
| UniProt: | Q12849 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
