Description
Human HMGB2 Recombinant Protein (N-His)
Human HMGB2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly2-Pro187, with an N-terminal His tag. Predicted molecular weight: 23.43 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. High mobility group protein B2 (HMGB2) is a ~24 kDa protein. Multifunctional protein with various roles in different cellular compartments. For research use only.
May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes. Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor binding and/or bringing distant regulatory sequences into close proximity.
| Product Name: | Human HMGB2 Recombinant Protein (N-His) |
| SKU: | GXRP01313 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | HMGB2, High mobility group protein 2, HMG-2, HMG2, High mobility group protein B2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly2-Pro187 |
| Calculated MW: | 23.43 kDa |
| UniProt: | P26583 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
