Description
Human HPGD Recombinant Protein (N-His)
Human HPGD Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Gln266, with an N-terminal His tag. Predicted molecular weight: 31.14 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. 15-hydroxyprostaglandin dehydrogenase [NAD(+)] is a ~28 kDa protein. Catalyzes the NAD-dependent dehydrogenation (oxidation) of a broad array of hydroxylated polyunsaturated fatty acids (mainly eicosanoids and docosanoids, including prostaglandins, lipoxins and resolvins), yielding their corresponding keto (oxo) metabolites. For research use only.
Decreases the levels of the pro-proliferative prostaglandins such as prostaglandin E2 (whose activity is increased in cancer because of an increase in the expression of cyclooxygenase 2) and generates oxo-fatty acid products that can profoundly influence cell function by abrogating pro-inflammatory cytokine expression. Converts resolvins E1, D1 and D2 to their oxo products, which represents a mode of resolvin inactivation. Resolvin E1 plays important roles during the resolution phase of acute inflammation, while resolvins D1 and D2 have a unique role in obesity-induced adipose inflammation.
| Product Name: | Human HPGD Recombinant Protein (N-His) |
| SKU: | GXRP11275 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 15-PGDH, 15-hydroxyprostaglandin dehydrogenase [NAD(+)], EC:1.1.1.-, EC:1.1.1.141, EC:1.1.1.232, Eicosanoid/docosanoid dehydrogenase [NAD(+)], HPGD, PGDH1, Prostaglandin dehydrogenase 1, SDR36C1, Short chain dehydrogenase/reductase family 36C member 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Gln266 |
| Calculated MW: | 31.14 kDa |
| UniProt: | P15428 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
