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Human IDH3B Recombinant Protein (N-His)
Key Features

Human IDH3B Recombinant Protein (N-His) (GXRP07374)

SKU GXRP07374
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human IDH3B Recombinant Protein (N-His)

Human IDH3B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser48-Ser385, with an N-terminal His tag. Predicted molecular weight: 39.70 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B) is a ~42 kDa protein. Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. For research use only.

The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.

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