Description
Human IGF2BP3 Recombinant Protein (N-His)
Human IGF2BP3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn2-Ile343, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) is a ~63 kDa protein. RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). For research use only.
This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells.
| Product Name: | Human IGF2BP3 Recombinant Protein (N-His) |
| SKU: | GXRP00038 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Insulin-like growth factor 2 mRNA-binding protein 3, VICKZ3, IGF2BP3, IMP3, KH domain-containing protein overexpressed in cancer, IMP-3, VICKZ family member 3, IGF-II mRNA-binding protein 3, KOC1, hKOC, IGF2 mRNA-binding protein 3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asn2-Ile343 |
| UniProt: | O00425 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
