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Human IL-5 Polyclonal Antibody (CAB21170)

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SKU:
CAB21170
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human Mouse Rat Other (Wide Range Predicted)
Host Species:
Rabbit
Synonyms:
EDF TRF IL-5 Human IL-5
€96 - €370
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Description

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Human IL-5 Polyclonal Antibody (CAB21170)

The Human IL-5 Polyclonal Antibody (CAB21170) is a high-quality antibody developed for reliable detection and analysis of target proteins. This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat, Other (Wide Range Predicted) samples.

Product Name:Human IL-5 Polyclonal Antibody
SKU:CAB21170
Size:100μL, 20μL
Reactivity:Human, Mouse, Rat, Other (Wide Range Predicted)
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:EDF, TRF, IL-5, Human IL-5
Positive Sample:Recombinant Human IL-5 Protein
Cellular Localization:Secreted.
Calculated MW:15kDa
Observed MW:18-23kDa

This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

Purification MethodAffinity purification
Gene ID3567
RRIDIF
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of Recombinant Human IL-5 Protein (RP01316), using Human IL-5 Rabbit pAb (CAB21170) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 10ng/5ng per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 0.8s.

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