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Human Interferon alpha 8 / IFN-alpha B2 ELISA Kit

SKU:
HUFI02109
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P32881
Sensitivity:
4.688pg/ml
Range:
7.813-500pg/ml
ELISA Type:
Sandwich
Synonyms:
IFNA8, IFN-alpha-8, IFN-alphaB, interferon alpha type 201, interferon alpha-8, Interferon alpha-B, interferon alpha-B', Interferon alpha-B2, interferon, alpha 8, LeIF B, Interferon alpha-B, LeIF B, Interferon alpha-B2
Reactivity:
Human
Research Area:
Immunology
€599
Frequently bought together:

Description

Human Interferon alpha 8 / IFN-alpha B2 ELISA

Interferon alpha 8 / IFN-alpha B2 belongs to the type I interferon family and is highly expressed in skin lesions and peripheral blood leukocytes following T cell activation. Interferon alpha 8 / IFN-alpha B2 can block cellular proliferation and also inhibit the production of tumor necrosis factor alpha and nitric oxide synthase induced by endotoxins. Interferon alpha 8 / IFN-alpha B2 exerts its biological effect by binding to a cell surface receptor complex composed of interferon gamma receptor, which leads to the activation of Jak / Stat signaling pathway. Diseases associated with Interferon alpha 8 / IFN-alpha B2 are leukocyte adhesion deficiency type I, recurrent infections, autoimmune disorders and immunodeficiency.

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