Description
Human IRF4 Recombinant Protein (N-His)
Human IRF4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu130-Glu451, with an N-terminal His tag. Predicted molecular weight: 39.25 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Interferon regulatory factor 4 (IRF4) is a ~51 kDa protein. Transcriptional activator. For research use only.
Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
| Product Name: | Human IRF4 Recombinant Protein (N-His) |
| SKU: | GXRP02313 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | IRF-4, NF-EM5, MUM1, LSIRF, IRF4, Multiple myeloma oncogene 1, Interferon regulatory factor 4, Lymphocyte-specific interferon regulatory factor |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu130-Glu451 |
| Calculated MW: | 39.25 kDa |
| UniProt: | Q15306 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
