Description
Human IRS4 Recombinant Protein (N-His)
Human IRS4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly76-Gly362, with an N-terminal His tag. Predicted molecular weight: 34.70 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Insulin receptor substrate 4 is a ~133 kDa protein. Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity, such as insulin receptor, IGF1R and FGFR1, and a complex network of intracellular signaling molecules containing SH2 domains. For research use only.
Involved in the IGF1R mitogenic signaling pathway. Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis. Interaction with GRB2 enhances insulin-stimulated mitogen-activated protein kinase activity. May be involved in nonreceptor tyrosine kinase signaling in myoblasts.
| Product Name: | Human IRS4 Recombinant Protein (N-His) |
| SKU: | GXRP11116 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 160 kDa phosphotyrosine protein, IRS-4, IRS4, Insulin receptor substrate 4, Phosphoprotein of 160 kDa, pp160, py160 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly76-Gly362 |
| Calculated MW: | 34.70 kDa |
| UniProt: | O14654 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
