Description
Human ITGA3/CD49c Recombinant Protein (N-His)
Human ITGA3/CD49c Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg463-Asp757, with an N-terminal His tag. Predicted molecular weight: 35.81 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Integrin alpha-3 (ITGA3/CD49c) is a ~116 kDa protein. Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. For research use only.
Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
| Product Name: | Human ITGA3/CD49c Recombinant Protein (N-His) |
| SKU: | GXRP08708 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Integrin alpha-3, CD49 antigen-like family member C, FRP-2, Galactoprotein B3, GAPB3, VLA-3 subunit alpha, CD49c, Integrin alpha-3 heavy chain, Integrin alpha-3 light chain, ITGA3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg463-Asp757 |
| Calculated MW: | 35.81 kDa |
| UniProt: | P26006 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
