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Human ITPA Recombinant Protein (N-His)
Key Features

Human ITPA Recombinant Protein (N-His) (GXRP03498)

SKU GXRP03498
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human ITPA Recombinant Protein (N-His)

Human ITPA Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala3-Arg180, with an N-terminal His tag. Predicted molecular weight: 22.03 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Inosine triphosphate pyrophosphatase (ITPA) is a ~21 kDa protein. Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. For research use only.

The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

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