Description
Human JAK1 Recombinant Protein (N-His)
Human JAK1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Pro32-Phe286, with an N-terminal His tag. Predicted molecular weight: 32.04 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tyrosine-protein kinase JAK1 is a ~133 kDa protein. Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. For research use only.
Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Kinase partner for the type I interferon receptor IFNAR2. In response to interferon-binding to IFNAR1-IFNAR2 heterodimer, phosphorylates and activates its binding partner IFNAR2, creating docking sites for STAT proteins. Directly phosphorylates STAT proteins but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors.
| Product Name: | Human JAK1 Recombinant Protein (N-His) |
| SKU: | GXRP01249 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | JAK1B, JAK1, Janus kinase 1, Tyrosine-protein kinase JAK1, JAK1A, JAK-1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Pro32-Phe286 |
| Calculated MW: | 32.04 kDa |
| UniProt: | P23458 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
