Description
Human KATNA1 Recombinant Protein (N-His)
Human KATNA1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Lys167, with an N-terminal His tag. Predicted molecular weight: 21.57 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Katanin p60 ATPase-containing subunit A1 (KATNA1) is a ~55 kDa protein. Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. For research use only.
Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
| Product Name: | Human KATNA1 Recombinant Protein (N-His) |
| SKU: | GXRP00238 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Katanin p60 ATPase-containing subunit A1, p60 katanin, KATNA1, Katanin p60 subunit A1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Lys167 |
| Calculated MW: | 21.57 kDa |
| UniProt: | O75449 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |