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Human KCNA4 Recombinant Protein (N-His)
Key Features

Human KCNA4 Recombinant Protein (N-His) (GXRP10574)

SKU GXRP10574
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human KCNA4 Recombinant Protein (N-His)

Human KCNA4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu176-Pro300, with an N-terminal His tag. Predicted molecular weight: 17.43 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Potassium voltage-gated channel subfamily A member 4 is a ~73 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. For research use only.

Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation.

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