Description
Human KCNA4 Recombinant Protein (N-His-SUMO)
Human KCNA4 Recombinant Protein (N-His-SUMO) is a recombinant protein expressed in E. coli, spanning Glu176-Gly274, with an N-terminal His-SUMO tag. Predicted molecular weight: 24.17 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Potassium voltage-gated channel subfamily A member 4 (KCNA4/Kv1.4 K+ channel) is a ~73 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. For research use only.
Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation.
| Product Name: | Human KCNA4 Recombinant Protein (N-His-SUMO) |
| SKU: | GXRP05710 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Voltage-gated potassium channel HBK4, Voltage-gated potassium channel HK1, HPCN2, Voltage-gated K(+) channel HuKII, Potassium voltage-gated channel subfamily A member 4, KCNA4L, KCNA4, Voltage-gated potassium channel subunit Kv1.4 |
| Tag: | N-His-SUMO |
| Expression Host: | E. coli |
| Protein Length: | Glu176-Gly274 |
| Calculated MW: | 24.17 kDa |
| UniProt: | P22459 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
