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Human KCNIP4 Recombinant Protein (N-His)
Key Features

Human KCNIP4 Recombinant Protein (N-His) (GXRP13237)

SKU GXRP13237
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human KCNIP4 Recombinant Protein (N-His)

Human KCNIP4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser56-Ile250, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Kv channel-interacting protein 4 is a ~28 kDa protein. Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. For research use only.

Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Modulates KCND3/Kv4.3 currents. Isoform 4 does not increase KCND2 expression at the cell membrane. Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.

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