Description
Human KMT5A Recombinant Protein (N-His)
Human KMT5A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu263-His393, with an N-terminal His tag. Predicted molecular weight: 17.14 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. N-lysine methyltransferase KMT5A is a ~42 kDa protein. Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. For research use only.
Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis.
| Product Name: | Human KMT5A Recombinant Protein (N-His) |
| SKU: | GXRP04191 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Histone-lysine N-methyltransferase KMT5A, PR/SET07, SETD8, SET8, PR-Set7, Lysine N-methyltransferase 5A, PRSET7, N-lysine methyltransferase KMT5A, SET domain-containing protein 8, Lysine-specific methylase 5A, H4-K20-HMTase KMT5A, SET07, KMT5A, PR/SET domain-containing protein 07 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu263-His393 |
| Calculated MW: | 17.14 kDa |
| UniProt: | Q9NQR1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
