Description
Human KMT5A Recombinant Protein (N-His)
Human KMT5A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser231-His393, with an N-terminal His tag. Predicted molecular weight: 20.82 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. N-lysine methyltransferase KMT5A is a ~42 kDa protein. Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. For research use only.
Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis.
| Product Name: | Human KMT5A Recombinant Protein (N-His) |
| SKU: | GXRP12005 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | EC:2.1.1.-, EC:2.1.1.361, H4-K20-HMTase KMT5A, Histone-lysine N-methyltransferase KMT5A, KMT5A, Lysine N-methyltransferase 5A, Lysine-specific methylase 5A, N-lysine methyltransferase KMT5A, PR-Set7, PR/SET domain-containing protein 07, PR/SET07, PRSET7, SET domain-containing protein 8, SET07, SET8, SETD8 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser231-His393 |
| Calculated MW: | 20.82 kDa |
| UniProt: | Q9NQR1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
