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Human LAP3 Recombinant Protein (N-His)
Key Features

Human LAP3 Recombinant Protein (N-His) (GXRP01355)

SKU GXRP01355
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human LAP3 Recombinant Protein (N-His)

Human LAP3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala320-Ala519, with an N-terminal His tag. Predicted molecular weight: 24.19 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cytosol aminopeptidase (LAP3) is a ~56 kDa protein. Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. For research use only.

The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.

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