Description
Human LRPPRC Recombinant Protein (N-His)
Human LRPPRC Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr385-Asp725, with an N-terminal His tag. Predicted molecular weight: 41.31 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Leucine-rich PPR motif-containing protein, mitochondrial is a ~157 kDa protein. May play a role in RNA metabolism in both nuclei and mitochondria. For research use only.
In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. Positively modulates nuclear export of mRNAs containing the EIF4E sensitivity element (4ESE) by binding simultaneously to both EIF4E and the 4ESE and acting as a platform for assembly for the RNA export complex. Also binds to exportin XPO1/CRM1 to engage the nuclear pore and traffic the bound mRNAs to the cytoplasm. May bind mature mRNA in the nucleus outer membrane.
| Product Name: | Human LRPPRC Recombinant Protein (N-His) |
| SKU: | GXRP10789 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 130 kDa leucine-rich protein, GP130, LRP 130, LRP130, LRPPRC, Leucine-rich PPR motif-containing protein, mitochondrial |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr385-Asp725 |
| Calculated MW: | 41.31 kDa |
| UniProt: | P42704 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
