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Human LRRFIP1 Recombinant Protein (N-His)
Key Features

Human LRRFIP1 Recombinant Protein (N-His) (GXRP02402)

SKU GXRP02402
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human LRRFIP1 Recombinant Protein (N-His)

Human LRRFIP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp615-Ser735, with an N-terminal His tag. Predicted molecular weight: 15.15 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) is a ~89 kDa protein. Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. For research use only.

May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

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