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Human LTK Recombinant Protein (N-His)
Key Features

Human LTK Recombinant Protein (N-His) (GXRP10718)

SKU GXRP10718
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human LTK Recombinant Protein (N-His)

Human LTK Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser67-Asn380, with an N-terminal His tag. Predicted molecular weight: 33.6 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Leukocyte tyrosine kinase receptor is a ~91 kDa protein. Receptor with a tyrosine-protein kinase activity. For research use only.

Following activation by ALKAL1 or ALKAL2 ligands at the cell surface, transduces an extracellular signal into an intracellular response. Ligand-binding to the extracellular domain induces tyrosine kinase activation, leading to activation of the mitogen-activated protein kinase (MAPK) pathway. Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif. The exact function of this protein is not known; studies with chimeric proteins demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival.

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