Description
Human LTN1 Recombinant Protein (N-His)
Human LTN1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu1587-Phe1766, with an N-terminal His tag. Predicted molecular weight: 22.96 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. E3 ubiquitin-protein ligase listerin is a ~200 kDa protein. E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. For research use only.
Within the RQC complex, LTN1 is recruited to stalled 60S ribosomal subunits by NEMF and mediates ubiquitination of stalled nascent chains. Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product.
| Product Name: | Human LTN1 Recombinant Protein (N-His) |
| SKU: | GXRP11243 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | C21orf10, C21orf98, E3 ubiquitin-protein ligase listerin, EC:2.3.2.27, KIAA0714, LTN1, RING finger protein 160, RING-type E3 ubiquitin transferase listerin, RNF160, ZNF294, Zinc finger protein 294 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu1587-Phe1766 |
| Calculated MW: | 22.96 kDa |
| UniProt: | O94822 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
