Description
Human MACROH2A2 Recombinant Protein (N-His)
Human MACROH2A2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly182-Lys372, with an N-terminal His tag. Predicted molecular weight: 22.98 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Core histone macro-H2A.2 (MACROH2A2) is a ~40 kDa protein. Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. For research use only.
Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
| Product Name: | Human MACROH2A2 Recombinant Protein (N-His) |
| SKU: | GXRP05015 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Histone macroH2A2, H2AFY2, Core histone macro-H2A.2, mH2A2, MACROH2A2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly182-Lys372 |
| Calculated MW: | 22.98 kDa |
| UniProt: | Q9P0M6 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
