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Human MAFK Recombinant Protein (N-His)
Key Features

Human MAFK Recombinant Protein (N-His) (GXRP07390)

SKU GXRP07390
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human MAFK Recombinant Protein (N-His)

Human MAFK Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ser156, with an N-terminal His tag. Predicted molecular weight: 19.55 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Transcription factor MafK is a ~17 kDa protein. Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. For research use only.

However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1/NRF1, NFE2L2/NRF2 and NFE2L3/NRF3, and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.

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