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Human MCK10 / DDR1 ELISA Kit

SKU:
HUFI01469
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q08345
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
DDR1, Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, Protein-tyrosine kinase 3A, Mammary carcinoma kinase 10, MCK-10, HGK2, Discoidin receptor tyrosine kinase, Tyrosine kinase DDR, TRK E, Protein-tyrosine k
Reactivity:
Human
Research Area:
Cell Biology
€599
Frequently bought together:

Description

Human MCK10 / DDR1 ELISA

DDR1 (Discoidin Domain Receptor Tyrosine Kinase 1) is a member of the tyrosine kinase receptor family with similarity to dictyostelium discoideum protein discoidin I in its extracellular domain, and it is activated by many forms of collagen. DDR1 expression is found in epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. It has also been discovered to be widely overexpressed in several human cancer specimens in studies. Receptor tyrosine kinases are involved in the communication between cells and their microenvironment. These kinases are concerned with cell growth, differentiation, and metabolism regulation. Alport syndrome and meninges sarcoma are examples of diseases linked to DDR1. Actin nucleation by ARP-WASP complex and ERK signaling are two related pathways.

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