Description
Human MCOLN3 Recombinant Protein (N-His)
Human MCOLN3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn84-His283, with an N-terminal His tag. Predicted molecular weight: 25.56 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Mucolipin-3 is a ~64 kDa protein. Nonselective cation channel probably playing a role in the regulation of membrane trafficking events. For research use only.
Acts as a Ca(2+)-permeable cation channel with inwardly rectifying activity. Mediates release of Ca(2+) from endosomes to the cytoplasm, contributes to endosomal acidification and is involved in the regulation of membrane trafficking and fusion in the endosomal pathway. Also permeable to Mg(2+), Na(+) and K(+). Does not seem to act as mechanosensory transduction channel in inner ear sensory hair cells.
| Product Name: | Human MCOLN3 Recombinant Protein (N-His) |
| SKU: | GXRP13456 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | MCOLN3, Mucolipin-3, TRPML3, Transient receptor potential channel mucolipin 3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asn84-His283 |
| Calculated MW: | 25.56 kDa |
| UniProt: | Q8TDD5 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
