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Human MCRS1 Recombinant Protein (N-His)
Key Features

Human MCRS1 Recombinant Protein (N-His) (GXRP06383)

SKU GXRP06383
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human MCRS1 Recombinant Protein (N-His)

Human MCRS1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln344-Gln462, with an N-terminal His tag. Predicted molecular weight: 15.79 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Microspherule protein 1 (MCRS1) is a ~51 kDa protein. Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. For research use only.

As part of the NSL complex, may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA.

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